WebHemicholinium-3 C24H34Br2N2O4 CID 9399 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, … Hemicholinium-3 (HC3), also known as hemicholine, is a drug which blocks the reuptake of choline by the high-affinity choline transporter (ChT; encoded in humans by the gene SLC5A7) at the presynapse. The reuptake of choline is the rate-limiting step in the synthesis of acetylcholine; hence, … Visualizza altro Hemicholinium-3 is highly toxic because it interferes with cholinergic neurotransmission. The LD50 of hemicholinium-3 for mice is about 35 μg. Visualizza altro • Triethylcholine • Vesamicol Visualizza altro
Hemicholinium-3 - an overview ScienceDirect Topics
WebIn the presence of hemicholinium-3 (HC-3, 5 μM), extracellular choline-dependent ACh synthesis appeared to consist of two different components. The first component (saturated at up to 50 μM choline) was dependent on the HC-3-resistant choline uptake system having a low capacity for choline in comparison with the high-affinity choline uptake system … Web1 mag 1988 · hemicholinium (HC-3, 20 PM; filled circles) are 1-2 min. The same pattern of stimulation was re- shown on a logarithmic scale. No stimulation was peated after tOmin of exposure to 20 ELM hcmi- hellpup ff14
The mechanism of action of the hemicholiniums - PubMed
WebHemicholinium (HC-3), a neuromuscular blocking agent which inhibits the synthesis and the release of acetylcholine (ACh) was investigated for its effects both on [ 14 C]ACh synthesis from [2- 14 C]pyruvate or [6- 14 C]glucose and on [ 3 H]choline uptake in purified rat striatal synaptosomes. WebHemicholinium C24H34N2O4+2 CID 3585 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. WebIni memiliki efek yang lebih kecil pada sistem penyerapan afinitas rendah. Karena kolin adalah salah satu komponen ACETILCHOLINE, pengobatan dengan hemicholinium … lake tahoe golf celebrity tournament