Ptk7 fc chimera

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August undefined, 2024

WebJul 1, 2024 · Our CAR-engineered T cells specifically bound to recombinant human-PTK7 Fc chimera. PTK7 CAR Jurkat T cells became activated in the presence of PTK7-expressing … WebRecombinant Mouse PTK7/CCK4 Fc Chimera (Catalog # 10333-TK) binds Biotinylated Recombinant Mouse Wnt-3a (Catalog # BT1324). The ED 50 for this effect is 8-48 μg/mL. …

The Cell Polarity PTK7 Receptor Is Expressed in Myeloid Cells and …

WebRecombinant Mouse PTK7/CCK4 Fc Chimera Protein, CF (10333-TK): Novus Biologicals Recombinant Mouse PTK7/CCK4 Fc Chimera Protein, CF. Backed by our 100% Guarantee. … Web(PTK7-01H) Recombinant Human PTK7 Protein, Fc-tagged Project Description: Protein Labeling (optional): Note: There will be extra charge for optional service! Optional Service: … intf-type

PTK7 (CCK-4) Antibody, anti-human - Miltenyi Biotec

WebProduct Specifications. >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining. <0.01 EU per 1 μg of the protein by the LAL method. Measured by its binding ability in a functional ELISA. When Recombinant Human PD-1 Fc Chimera is immobilized at 0.1 µg/mL (100 µL/well), Recombinant Human B7 ... WebProtein tyrosine kinase 7 (PTK7), also known as colon carcinoma kinase 4 (CCK4), is a receptor tyrosine kinase (RTK) involved in colon carcinoma development and/or … WebResistance to apoptosis correlated to PTK7 overexpression is recapitulated in vitro and can be partially decreased by a recombinant soluble PTK7-Fc protein . Role of PTK7 overexpression in resistance to apoptosis induced by anthracycline-based chemotherapy has also been described in breast cancer . A PTK7-dependent resistance to apoptosis has ... intf traveling

The cell polarity PTK7 receptor acts as a modulator of the ...

PTK7/CCK4 Products: R&D Systems

WebSep 30, 2010 · The recombinant PTK7-Fc protein that composes the extracellular region of PTK7 (soluble PTK7) fused to the Fc region of IgG1 was produced in COS cells using a protocol already used for recombinant Nectin4-Fc. 21 Of note, both Baf3 and TF1 cell lines used for the study do not express multidrug resistance phenotype (data not shown). WebThe Anti-PTK7 (CCK-4) antibody (clone 188B) recognizes human protein tyrosine kinase-7 (PTK7). PTK7, also known as colon carcinoma kinase-4 (CCK-4), is a receptor protein tyrosine kinase (RPTK)–like molecule that contains a catalytically inactive tyrosine kinase domain. PTK7 was identified to be important for neural development as a regulator of … new home construction allentown paWebProtein tyrosine kinases (PTKs), including transmembrane receptor tyrosine kinases and cytoplasmic nonreceptor tyrosine kinases, play vital roles in a variety of cellular … new home construction atlanta

"WebHuman PTK7 / CCK4 protein (9799-TK) is manufactured by R&D Systems, over 95% purity. Reproducible results in bioactivity assays. Learn More... " - Ptk7 fc chimera

Ptk7 fc chimera

Recombinant Mouse PTK7/CCK4 Fc Chimera Protein, CF

WebProduct Specifications for Recombinant Human PTK7/CCK4 Fc Chimera Protein, CF Source Human embryonic kidney cell, HEK293-derived human PTK7/CCK4 protein Purity >95%, by … WebJul 22, 2024 · Purpose: Triple-negative breast cancer (TNBC), the most aggressive subtype of breast cancer, is associated with high invasiveness, high metastatic occurrence and poor prognosis. Protein tyrosine kinase 7 (PTK7) plays an important role in multiple cancers. However, the role of PTK7 in TNBC has not been well addressed.

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WebDescription. Measured by its binding ability in a functional ELISA. In a 100 µL reaction mixture containing biotinylated Recombinant Mouse Wnt-3a at 50 ng/mL and Recombinant Human PTK7/CCK4 Chimera dilutions, the concentration of Recombinant Human PTK7/CCK4 Fc Chimera that produces 50% of the maximal binding response is 4-20 μg/mL. WebRecombinant Mouse PTK7/CCK4 Fc Chimera (Catalog # 10333-TK) binds Biotinylated Recombinant Mouse Wnt-3a (Catalog # BT1324). The ED 50 for this effect is 8-48 μg/mL. …

WebSource/Expression System NS0-derived Recombinant Mouse PTK7/CCK4 Fc Chimera Protein, CF; NCBI Full Gene Name PTK7 protein tyrosine kinase 7, protein tyrosine kinase 7 (inactive) NCBI Gene Aliases mPTK7/CCK4, CCK-4, 8430404F20Rik, CCK4, mPTK7/CCK, chz; Specifications/Features WebMeasured by its binding ability in a functional ELISA. In a 100 µL reaction mixture containing biotinylated Recombinant Mouse Wnt-3a (Catalog # BT1324) at 50 ng/mL and Recombinant Human PTK7/CCK4 Chimera dilutions, the concentration of Recombinant Human PTK7/CCK4 Fc Chimera that produces 50% of the maximal binding response is 4-20 μg/mL.

WebROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and … WebThe Anti-PTK7 (CCK-4) antibody (clone 188B) recognizes human protein tyrosine kinase-7 (PTK7). PTK7, also known as colon carcinoma kinase-4 (CCK-4), is a receptor protein tyrosine kinase (RPTK)–like molecule that contains a catalytically inactive tyrosine kinase domain. PTK7 was identified to be important for neural development as a regulator of …

WebHuman PTK7 is a 1040 amino acid (aa) glycoprotein containing a 674 aa extracellular domain (ECD), a 21 aa transmembrane domain, and a 345 aa cytoplasmic tyrosine kinase …

WebAug 17, 2024 · PTK7 expression is detected in relapsed OC primary tumors and correlates with poor prognosis. Pan-cancer TCGA analysis of PTK7 expression in the seven most common cancers in women (breast ... int f trueWebBackground: PTK7/CCK4. Protein tyrosine kinase 7 (PTK7), also known as colon carcinoma kinase 4 (CCK4), is a member of the receptor tyrosine kinase superfamily (1, 2). PTK7 is a … new home construction argyle txWebJul 1, 2024 · Our CAR-engineered T cells specifically bound to recombinant human-PTK7 Fc chimera. PTK7 CAR Jurkat T cells became activated in the presence of PTK7-expressing … new home construction bargersville indianaWebMar 21, 2024 · Molecular function for PTK7 Gene according to UniProtKB/Swiss-Prot. Function: Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both … new home construction avon ohioWebView 7 PTK7/CCK4 products. Bio-Techne offers high-quality reagents instruments, custom manufacturing, and testing services. Skip to main content United States - (English) Country/Region selector. Please enter your country/region. Select Preferred Language. English. 简体中文 (800) 343-7475 ... new home construction alexandria vaWebNov 20, 2009 · In the absence of known inhibitor of PTK7, we produced a soluble recombinant PTK7-Fc protein that efficiently competes for PTK7 functions in cell migration and survival assays in cell lines and primary AML samples. These data were confirmed using a shRNA strategy. We conclude that PTK7 is a PCP component expressed in the myeloid … new home construction atlanta areaWebIn a 100 µL reaction mixture containing biotinylated Recombinant Mouse Wnt-3a at 50 ng/mL and Recombinant Human PTK7/CCK4 Chimera dilutions, the concentration of … new home construction anchorage alaska